Good morning, and happy Thursday! While you were busy living your life, the French baguette was awarded special protection status with a spot on the United Nations' list of Intangible Cultural Heritage. It now keeps company with other culinary items like Neapolitan pizza, kimchi, and Arabic coffee…but hey, where’s the love for the croissant? First time reading? Sign up here. In Today’s Brief
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Alzheimer’s drug trial resultsResults from a phase 3 clinical trial showed that an experimental drug to treat Alzheimer’s disease helped slow cognitive decline but may carry a risk of adverse side effects. Japanese pharmaceutical company Eisai and American biotech company Biogen conducted the trial to test lecanemab, which the companies have claimed reduces the rate of cognitive decline on a clinical dementia scale by 27% compared to a placebo. According to the recent study published in the New England Journal of Medicine, the drug “reduced markers of amyloid in early Alzheimer’s disease and resulted in moderately less decline on measures of cognition and function than placebo at 18 months but was associated with adverse events.” The trial enrolled nearly 1,800 participants with early-stage Alzheimer’s. While the Alzheimer's Association said the data confirms that lecanemab “can meaningfully change the course of the disease,” trial results showed that nearly 13% of patients who received it experienced brain swelling. |
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House passes bill to avert rail strikeTo avert a potential rail strike, the House of Representatives passed a resolution that would force unions to accept a tentative agreement reached earlier this year between railroad managers and their workers. Lawmakers voted 290-137 to pass the measure, which provides workers with 24% raises over five years and allows them to take time off for medical appointments without being penalized. House members also voted 221-207 to pass a separate measure that would give rail workers seven days of paid sick leave per year, which was one of the concerns that unions had with the tentative agreement that the White House brokered in September. President Biden praised the House and said that “without action this week, disruptions to our auto supply chains, our ability to move food to tables, and our ability to remove hazardous waste from gasoline refineries will begin,” adding that the “Senate must move quickly” to send a bill to his desk to be signed into law. |
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Fleetwood Mac’s Christine McVie diesChristine McVie, who sang and played keyboard in the British-American rock band Fleetwood Mac, passed away at age 79, according to a statement from her family. In a statement posted to Facebook, the band said: “There are no words to describe our sadness at the passing of Christine McVie. She was truly one-of-a-kind, special and talented beyond measure. She was the best musician anyone could have in their band and the best friend anyone could have in their life.” While a cause of death was not given, McVie’s family said that she died at a hospital “following a short illness.” McVie joined Fleetwood Mac in 1970 and remained part of the band until her departure following their 1998 reunion tour, and rejoined in 2014. She penned and sang several songs in the band’s catalog, including “Everywhere,” “Say You Love Me,” “You Make Loving Fun,” “Don’t Stop,” and “Little Lies.” |
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Looking Back…On December 1st: Rosa Parks is arrested after she refuses to give up her bus seat in Montogomery, AL (1955); Ford Motor Company institutes the world's first moving assembly line for the Model T (1913); Hugh Hefner publishes the first edition of Playboy magazine featuring Marilyn Monroe as the centerfold (1953); American actress and singer Bette Midler is born (1945). |
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